Topigen Pharmaceuticals, Respiratory Research

Discovery of ACH-000143: A Novel Potent and Peripherally Preferred Melatonin Receptor Agonist that Reduces Liver Triglycerides and Steatosis in Diet-Induced Obese Rats

The modulation of melatonin signaling in peripheral tissues holds promise for treating metabolic ailments like weight problems, diabetes, and nonalcoholic steatohepatitis. Right here, a number of benzimidazole derivatives have been recognized as novel agonists of the melatonin receptors MT1 and MT2. The lead compounds <b>10b</b>, <b>15a</b>, and <b>19a</b> demonstrated subnanomolar efficiency at MT1/MT2 receptors, excessive oral bioavailability in rodents, peripherally most popular publicity, and glorious selectivity in a broad panel of targets.

Two-month oral administration of <b>10b</b> in high-fat food plan rats led to a discount in physique weight achieve much like dapagliflozin with superior outcomes on hepatic steatosis and triglyceride ranges. An early toxicological evaluation indicated that <b>10b</b> (additionally codified as <b>ACH-000143</b>) was devoid of hERG binding, genotoxicity, and behavioral alterations at doses as much as 100 mg/kg p.o., supporting additional investigation of this compound as a drug candidate.

Intracerebellar infusion of an mGluR1/5 agonist enhances eyeblink conditioning

Cerebellar metabotropic glutamate receptor 1 (mGluR1) expressed by Purkinje cells could play an necessary function in learning-related cerebellar plasticity. Eyeblink conditioning (EBC) is a well-studied type of Pavlovian studying that engages discrete areas of cerebellar cortex and deep cerebellar nuclei. EBC is impaired in mGluR1 knockout mice. Right here, we present that infusion of the mGluR1/5 agonist DHPG into the lobulus simplex area of cerebellar cortex facilitates EBC in rats.

Infusion was made previous to Classes 1 and a couple of of EBC however the facilitatory results endured all through subsequent, noninfusion classes. The facilitatory results had been confined to frequency of eyeblink conditioned responses (CRs); there have been no results on amplitude or latency of CRs. There have been additionally no results on reflexive responding to the tone conditioned stimulus or eyelid stimulation unconditioned stimulus.

The present outcomes present additional proof that cerebellar mGluR1 performs a job in cerebellar-dependent associative studying and complement earlier research utilizing mGluR1 knockout mice. (PsycInfo Database Report (c) 2021 APA, all rights reserved).

Analysis of adenosine A1 receptor agonists as neuroprotective countermeasures in opposition to Soman intoxication in rats

Soman, an organophosphorus (OP) compound, disrupts nervous system perform via inactivation of acetylcholinesterase (AChE), the enzyme that breaks down acetylcholine at synapses. Left untreated, a state of extended seizure exercise (standing epilepticus, SE) is induced, inflicting widespread neuronal injury and related cognitive and behavioral impairments.

Earlier analysis demonstrated that therapeutic stimulation of A1 adenosine receptors (A1ARs) can forestall or terminate soman-induced seizure. This examine examined the flexibility of three potent A1AR agonists to supply neuroprotection and, in the end, forestall observable cognitive and behavioral deficits following publicity to soman.

Sprague Dawley rats had been challenged with a seizure-inducing dose of soman (1.2 x LD₅₀) and handled 1 min later with one of many following A1AR agonists: (6)-Cyclopentyladenosine (CPA), 2-Chloro-N6-cyclopentyladenosine (CCPA) or (±)-5′-Chloro-5′-deoxy-ENBA (cdENBA). An energetic avoidance shuttle field job was used to guage locomotor responses to aversive stimuli at 3, 7 and 14 days post-exposure.

Animals handled with CPA, CCPA or cdENBA demonstrated the next variety of avoidance responses and a sooner response to the aversive stimulus than the soman/saline management group throughout all three classes. Findings recommend that A1AR agonism is a promising neuroprotective countermeasure, able to stopping the long-term deficits in studying and reminiscence which can be attribute of soman intoxication.

Obstetrician-Gynecologists’ Methods for Affected person Initiation and Upkeep of Antiobesity Therapy with Glucagon-Like Peptide-1 Receptor Agonists

Weight problems is a persistent illness affecting ladies at larger charges than males. In an obstetrics and gynecology setting, ceaselessly encountered obesity-related problems are polycystic ovary syndrome, fertility and being pregnant problems, and elevated danger of breast and gynecological cancers. Obstetrician-gynecologists (OBGYNs) are uniquely positioned to diagnose and deal with weight problems, given their function in ladies’s main well being care and the growing prevalence of obesity-related fertility and being pregnant problems.

The metabolic processes of body weight regulation are complicated, which makes weight-loss upkeep difficult, regardless of dietary modifications and train. Antiobesity drugs (AOMs) can facilitate weight reduction by concentrating on urge for food regulation. There are 4 AOMs presently accredited for long-term use in america, of which liraglutide 3.zero mg is among the many most efficacious.

Liraglutide 3.zero mg, a glucagon-like peptide-1 receptor agonist (GLP-1 RA), is superior to placebo in attaining weight reduction and enhancing cardiometabolic profile, in each scientific trial and real-world settings. As well as, ladies with fertility problems receiving liraglutide 1.8-3.zero mg can profit from improved ovarian perform and fertility. Liraglutide 3.zero mg is mostly nicely tolerated, however related to transient gastrointestinal negative effects, which will be mitigated.

On this overview, we current the dangers of weight problems and advantages of weight reduction for girls, and summarize scientific growth of GLP-1 RAs for weight administration. Lastly, we offer sensible recommendation and suggestions for OBGYNs to open the dialogue about body weight with their sufferers, provoke life-style modification and GLP-1 RA remedy, and assist them stick with these interventions to realize optimum weight reduction with related well being advantages.

Glucagon Like Peptide 1 Receptor Agonists for Focused Supply of Antisense Oligonucleotides to Pancreatic Beta Cell

The additional hepatic supply of antisense oligonucleotides (ASOs) stays a problem and hampers the widespread software of this highly effective class of therapeutic brokers. In that regard, pancreatic beta cells are a very enticing however difficult cell kind due to their pivotal function in diabetes and the truth that they’re refractory to uptake of unconjugated ASOs. To bypass this, we’ve got expanded our understanding of the construction exercise relationship of ASOs conjugated to Glucagon Like Peptide 1 Receptor (GLP1R) agonist peptide ligands.

We reveal the important thing function of the linker chemistry and its optimization to design maleimide primarily based conjugates with improved in vivo efficacy. As well as, truncation research and scoping of a various set of GLP1R agonists proved fruitful to establish extra concentrating on ligands efficacious in vivo together with native hGLP1(7-36)NH₂.

Monoclonal Antibody to BH3 Interacting Domain Death Agonist (Bid)
MAA629Hu21	Cloud-Clone	100ul	EUR 242

Monoclonal Antibody to BH3 Interacting Domain Death Agonist (Bid)
MBS2025623-INQUIRE	MyBiosource	INQUIRE	Ask for price

BH3 Interacting Domain Death Agonist (Bid) Monoclonal Antibody (Rat)
4-MAA629Ra21	Cloud-Clone	Ask for price Ask for price Ask for price Ask for price Ask for price	20ul 100ul 200ul 1ml 10ml
Description: A Mouse monoclonal antibody against Rat BH3 Interacting Domain Death Agonist (Bid)

β-Agonists ELISA Kit
AE81036SF-48T	Abebio	48T	EUR 345
Description: 0.05-4.05 ppb

β-Agonists ELISA Kit
AE81036SF-48Tests	Abebio	48 Tests	EUR 325
Description: Food Safety

β-Agonists ELISA Kit
AE81036SF-96T	Abebio	96T	EUR 610
Description: 0.05-4.05 ppb

β-Agonists ELISA Kit
AE81036SF-96Tests	Abebio	96 Tests	EUR 610
Description: Food Safety

ẞ-Agonists ELISA Kit
ELKFS047	ELK Biotech	96Tests	EUR 175

β-Agonists ELISA Kit
JOT-bAG-FS-48T	Jotbody	48T	EUR 390.4
Description: 0.05-4.05 ppb

β-Agonists ELISA Kit
JOT-bAG-FS-96T	Jotbody	96T	EUR 558.4
Description: 0.05-4.05 ppb

β-Agonists ELISA Kit
RDFS-bAG-48T	Reddot Biotech	48T	EUR 488
Description: Urine, tissue, feed, etc.

β-Agonists ELISA Kit
RDFS-bAG-96T	Reddot Biotech	96T	EUR 698
Description: Urine, tissue, feed, etc.

BH3 Interacting Domain Death Agonist (Bid) Monoclonal Antibody (Rat), PE
4-MAA629Ra21-PE	Cloud-Clone	Ask for price Ask for price Ask for price Ask for price Ask for price	20ul 100ul 200ul 1ml 10ml
Description: A Mouse monoclonal antibody against Rat BH3 Interacting Domain Death Agonist (Bid). This antibody is labeled with PE.

BH3 Interacting Domain Death Agonist (Bid) Monoclonal Antibody (Rat), APC
4-MAA629Ra21-APC	Cloud-Clone	Ask for price Ask for price Ask for price Ask for price Ask for price	20ul 100ul 200ul 1ml 10ml
Description: A Mouse monoclonal antibody against Rat BH3 Interacting Domain Death Agonist (Bid). This antibody is labeled with APC.

BH3 Interacting Domain Death Agonist (Bid) Monoclonal Antibody (Rat), Cy3
4-MAA629Ra21-Cy3	Cloud-Clone	Ask for price Ask for price Ask for price Ask for price Ask for price	20ul 100ul 200ul 1ml 10ml
Description: A Mouse monoclonal antibody against Rat BH3 Interacting Domain Death Agonist (Bid). This antibody is labeled with Cy3.

BH3 Interacting Domain Death Agonist (Bid) Monoclonal Antibody (Rat), HRP
4-MAA629Ra21-HRP	Cloud-Clone	Ask for price Ask for price Ask for price Ask for price Ask for price	20ul 100ul 200ul 1ml 10ml
Description: A Mouse monoclonal antibody against Rat BH3 Interacting Domain Death Agonist (Bid). This antibody is labeled with HRP.

BH3 Interacting Domain Death Agonist (Bid) Monoclonal Antibody (Rat), FITC
4-MAA629Ra21-FITC	Cloud-Clone	Ask for price Ask for price Ask for price Ask for price Ask for price	20ul 100ul 200ul 1ml 10ml
Description: A Mouse monoclonal antibody against Rat BH3 Interacting Domain Death Agonist (Bid). This antibody is labeled with FITC.

BH3 Interacting Domain Death Agonist (Bid) Monoclonal Antibody (Rat), APC-Cy7
4-MAA629Ra21-APC-Cy7	Cloud-Clone	Ask for price Ask for price Ask for price Ask for price Ask for price	20ul 100ul 200ul 1ml 10ml
Description: A Mouse monoclonal antibody against Rat BH3 Interacting Domain Death Agonist (Bid). This antibody is labeled with APC-Cy7.

PE-Linked Monoclonal Antibody to BH3 Interacting Domain Death Agonist (Bid)
MBS2107550-INQUIRE	MyBiosource	INQUIRE	Ask for price

APC/Cy7 Linked Monoclonal Antibody to BH3 Interacting Domain Death Agonist (Bid)
MBS2107549-INQUIRE	MyBiosource	INQUIRE	Ask for price

APC-Linked Monoclonal Antibody to BH3 Interacting Domain Death Agonist (Bid)
MBS2107551-INQUIRE	MyBiosource	INQUIRE	Ask for price

Cy3-Linked Monoclonal Antibody to BH3 Interacting Domain Death Agonist (Bid)
MBS2107552-INQUIRE	MyBiosource	INQUIRE	Ask for price

FITC-Linked Monoclonal Antibody to BH3 Interacting Domain Death Agonist (Bid)
MBS2107554-INQUIRE	MyBiosource	INQUIRE	Ask for price

HRP-Linked Monoclonal Antibody to BH3 Interacting Domain Death Agonist (Bid)
MBS2107555-INQUIRE	MyBiosource	INQUIRE	Ask for price

Botin-Linked Monoclonal Antibody to BH3 Interacting Domain Death Agonist (Bid)
MBS2107553-INQUIRE	MyBiosource	INQUIRE	Ask for price

BH3 Interacting Domain Death Agonist (Bid) Monoclonal Antibody (Rat), Biotinylated
4-MAA629Ra21-Biotin	Cloud-Clone	Ask for price Ask for price Ask for price Ask for price Ask for price	20ul 100ul 200ul 1ml 10ml
Description: A Mouse monoclonal antibody against Rat BH3 Interacting Domain Death Agonist (Bid). This antibody is labeled with Biotin.

Mouse Anti-β-Agonists monoclonal antibody, clone BA
CABT-ZB1141	Creative Diagnostics	1 mg	EUR 1250
Description: Mouse

VEGFR-2 (Human, monoclonal, agonistic)
mV1001.3m-h	Angio Proteomie	100ug	EUR 467.5

VEGFR-1 (Human, monoclonal, agonistic)
mV1004m-h	Angio Proteomie	100ug	EUR 467.5

IL1 beta Mouse Monoclonal Antibody
BF8021	Affbiotech	100ul	EUR 420

IKB beta Mouse Monoclonal Antibody
E10G20387	EnoGene	100 μl	EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

IKB beta Mouse Monoclonal Antibody
E10G20420	EnoGene	100 μl	EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

TGF beta, Monoclonal Antibody, Mouse
MBS555079-01mL	MyBiosource	0.1mL	EUR 265

TGF beta, Monoclonal Antibody, Mouse
MBS555079-5x01mL	MyBiosource	5x0.1mL	EUR 1030

IL1 beta Mouse Monoclonal Antibody
MBS9629040-01mL	MyBiosource	0.1mL	EUR 280

IL1 beta Mouse Monoclonal Antibody
MBS9629040-02mL	MyBiosource	0.2mL	EUR 325

IL1 beta Mouse Monoclonal Antibody
MBS9629040-5x02mL	MyBiosource	5x0.2mL	EUR 1305

GSK3 beta Mouse Monoclonal Antibody
E10G20684	EnoGene	100 μl	EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

GSK3 beta Mouse Monoclonal Antibody
E10G20685	EnoGene	100 μl	EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

GSK3 beta Mouse Monoclonal Antibody
E10G20686	EnoGene	100 μl	EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

GSK3 beta Mouse Monoclonal Antibody
E10G20717	EnoGene	100 μl	EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

GSK3 beta mouse monoclonal antibody
MBS9611253-005mL	MyBiosource	0.05mL	EUR 260

GSK3 beta mouse monoclonal antibody
MBS9611253-01mL	MyBiosource	0.1mL	EUR 325

GSK3 beta mouse monoclonal antibody
MBS9611253-02mL	MyBiosource	0.2mL	EUR 400

GSK3 beta mouse monoclonal antibody
MBS9611253-5x02mL	MyBiosource	5x0.2mL	EUR 1750

Hsp90 beta Mouse Monoclonal Antibody
E10G20433	EnoGene	100 μl	EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

Hsp90 beta Mouse Monoclonal Antibody
E10G20611	EnoGene	100 μl	EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

CAMK2 beta Mouse Monoclonal Antibody
E10G34377	EnoGene	100 μl	EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

beta Catenin Mouse Monoclonal Antibody
E10G20675	EnoGene	100 μl	EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

beta Catenin Mouse Monoclonal Antibody
E10G20757	EnoGene	100 μl	EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

Beta Amyloid, Monoclonal Antibody, Mouse
MBS555590-01mL	MyBiosource	0.1mL	EUR 435

Beta Amyloid, Monoclonal Antibody, Mouse
MBS555590-5x01mL	MyBiosource	5x0.1mL	EUR 1815

beta-actin Mouse Monoclonal Antibody
MBS8500449-01mg	MyBiosource	0.1mg	EUR 240

beta-actin Mouse Monoclonal Antibody
MBS8500449-01mLAF405L	MyBiosource	0.1mL(AF405L)	EUR 465

beta-actin Mouse Monoclonal Antibody
MBS8500449-01mLAF405S	MyBiosource	0.1mL(AF405S)	EUR 465

beta-actin Mouse Monoclonal Antibody
MBS8500449-01mLAF610	MyBiosource	0.1mL(AF610)	EUR 465

beta-actin Mouse Monoclonal Antibody
MBS8500449-01mLAF635	MyBiosource	0.1mL(AF635)	EUR 465

beta-actin Mouse Monoclonal Antibody
MBS8500761-01mg	MyBiosource	0.1mg	EUR 305

beta-actin Mouse Monoclonal Antibody
MBS8500761-01mLAF405L	MyBiosource	0.1mL(AF405L)	EUR 465

beta-actin Mouse Monoclonal Antibody
MBS8500761-01mLAF405S	MyBiosource	0.1mL(AF405S)	EUR 465

beta-actin Mouse Monoclonal Antibody
MBS8500761-01mLAF610	MyBiosource	0.1mL(AF610)	EUR 465

beta-actin Mouse Monoclonal Antibody
MBS8500761-01mLAF635	MyBiosource	0.1mL(AF635)	EUR 465

beta-Actin Mouse Monoclonal Antibody
MBS9610326-005mL	MyBiosource	0.05mL	EUR 190

beta-Actin Mouse Monoclonal Antibody
MBS9610326-01mL	MyBiosource	0.1mL	EUR 245

beta-Actin Mouse Monoclonal Antibody
MBS9610326-02mL	MyBiosource	0.2mL	EUR 310

beta-Actin Mouse Monoclonal Antibody
MBS9610326-1mL	MyBiosource	1mL	EUR 855

beta-Actin Mouse Monoclonal Antibody
MBS9610326-5x1mL	MyBiosource	5x1mL	EUR 3800

beta-actin Mouse Monoclonal Antibody
MBS8505145-01mg	MyBiosource	0.1mg	EUR 240

beta-actin Mouse Monoclonal Antibody
MBS8505145-01mLAF405L	MyBiosource	0.1mL(AF405L)	EUR 465

beta-actin Mouse Monoclonal Antibody
MBS8505145-01mLAF405S	MyBiosource	0.1mL(AF405S)	EUR 465

beta-actin Mouse Monoclonal Antibody
MBS8505145-01mLAF610	MyBiosource	0.1mL(AF610)	EUR 465

beta-actin Mouse Monoclonal Antibody
MBS8505145-01mLAF635	MyBiosource	0.1mL(AF635)	EUR 465

beta-actin Mouse Monoclonal Antibody
MBS8502008-01mg	MyBiosource	0.1mg	EUR 240

beta-actin Mouse Monoclonal Antibody
MBS8502008-01mLAF405L	MyBiosource	0.1mL(AF405L)	EUR 465

beta-actin Mouse Monoclonal Antibody
MBS8502008-01mLAF405S	MyBiosource	0.1mL(AF405S)	EUR 465

beta-actin Mouse Monoclonal Antibody
MBS8502008-01mLAF610	MyBiosource	0.1mL(AF610)	EUR 465

beta-actin Mouse Monoclonal Antibody
MBS8502008-01mLAF635	MyBiosource	0.1mL(AF635)	EUR 465

beta-actin Mouse Monoclonal Antibody
MBS8502767-01mg	MyBiosource	0.1mg	EUR 240

beta-actin Mouse Monoclonal Antibody
MBS8502767-01mLAF405L	MyBiosource	0.1mL(AF405L)	EUR 465

beta-actin Mouse Monoclonal Antibody
MBS8502767-01mLAF405S	MyBiosource	0.1mL(AF405S)	EUR 465

beta-actin Mouse Monoclonal Antibody
MBS8502767-01mLAF610	MyBiosource	0.1mL(AF610)	EUR 465

beta-actin Mouse Monoclonal Antibody
MBS8502767-01mLAF635	MyBiosource	0.1mL(AF635)	EUR 465

beta-actin Mouse Monoclonal Antibody
MBS9400220-01mL	MyBiosource	0.1mL	EUR 305

beta-actin Mouse Monoclonal Antibody
MBS9400220-5x01mL	MyBiosource	5x0.1mL	EUR 1230

beta-Actin Mouse Monoclonal Antibody
MBS9400413-005mL	MyBiosource	0.05mL	EUR 245

beta-Actin Mouse Monoclonal Antibody
MBS9400413-01mL	MyBiosource	0.1mL	EUR 305

beta-Actin Mouse Monoclonal Antibody
MBS9400413-5x01mL	MyBiosource	5x0.1mL	EUR 1230

beta-actin Mouse Monoclonal Antibody
MBS9400510-01mL	MyBiosource	0.1mL	EUR 305

beta-actin Mouse Monoclonal Antibody
MBS9400510-5x01mL	MyBiosource	5x0.1mL	EUR 1230

beta-tubulin Mouse Monoclonal Antibody
MBS8501125-01mg	MyBiosource	0.1mg	EUR 240

beta-tubulin Mouse Monoclonal Antibody
MBS8501125-01mLAF405L	MyBiosource	0.1mL(AF405L)	EUR 465

beta-tubulin Mouse Monoclonal Antibody
MBS8501125-01mLAF405S	MyBiosource	0.1mL(AF405S)	EUR 465

beta-tubulin Mouse Monoclonal Antibody
MBS8501125-01mLAF610	MyBiosource	0.1mL(AF610)	EUR 465

beta-tubulin Mouse Monoclonal Antibody
MBS8501125-01mLAF635	MyBiosource	0.1mL(AF635)	EUR 465

beta-tubulin Mouse Monoclonal Antibody
MBS8501126-01mg	MyBiosource	0.1mg	EUR 240

beta-tubulin Mouse Monoclonal Antibody
MBS8501126-01mLAF405L	MyBiosource	0.1mL(AF405L)	EUR 465

beta-tubulin Mouse Monoclonal Antibody
MBS8501126-01mLAF405S	MyBiosource	0.1mL(AF405S)	EUR 465

beta-tubulin Mouse Monoclonal Antibody
MBS8501126-01mLAF610	MyBiosource	0.1mL(AF610)	EUR 465

beta-tubulin Mouse Monoclonal Antibody
MBS8501126-01mLAF635	MyBiosource	0.1mL(AF635)	EUR 465

beta-Tubulin Mouse Monoclonal Antibody
MBS9610328-005mL	MyBiosource	0.05mL	EUR 190

beta-Tubulin Mouse Monoclonal Antibody
MBS9610328-01mL	MyBiosource	0.1mL	EUR 245

beta-Tubulin Mouse Monoclonal Antibody
MBS9610328-02mL	MyBiosource	0.2mL	EUR 310

beta-Tubulin Mouse Monoclonal Antibody
MBS9610328-1mL	MyBiosource	1mL	EUR 855

beta-Tubulin Mouse Monoclonal Antibody
MBS9610328-5x1mL	MyBiosource	5x1mL	EUR 3800

beta-tubulin Mouse Monoclonal Antibody
MBS8503945-01mg	MyBiosource	0.1mg	EUR 240

beta-tubulin Mouse Monoclonal Antibody
MBS8503945-01mLAF405L	MyBiosource	0.1mL(AF405L)	EUR 465

beta-tubulin Mouse Monoclonal Antibody
MBS8503945-01mLAF405S	MyBiosource	0.1mL(AF405S)	EUR 465

beta-tubulin Mouse Monoclonal Antibody
MBS8503945-01mLAF610	MyBiosource	0.1mL(AF610)	EUR 465

beta-tubulin Mouse Monoclonal Antibody
MBS8503945-01mLAF635	MyBiosource	0.1mL(AF635)	EUR 465

beta-Catenin Mouse Monoclonal Antibody
MBS8504093-01mg	MyBiosource	0.1mg	EUR 305

beta-Catenin Mouse Monoclonal Antibody
MBS8504093-01mLAF405L	MyBiosource	0.1mL(AF405L)	EUR 465

beta-Catenin Mouse Monoclonal Antibody
MBS8504093-01mLAF405S	MyBiosource	0.1mL(AF405S)	EUR 465

beta-Catenin Mouse Monoclonal Antibody
MBS8504093-01mLAF610	MyBiosource	0.1mL(AF610)	EUR 465

beta-Catenin Mouse Monoclonal Antibody
MBS8504093-01mLAF635	MyBiosource	0.1mL(AF635)	EUR 465

beta-Catenin Mouse Monoclonal Antibody
MBS8510428-01mg	MyBiosource	0.1mg	EUR 305

beta-Catenin Mouse Monoclonal Antibody
MBS8510428-01mLAF405L	MyBiosource	0.1mL(AF405L)	EUR 465

beta-Catenin Mouse Monoclonal Antibody
MBS8510428-01mLAF405S	MyBiosource	0.1mL(AF405S)	EUR 465

beta-Catenin Mouse Monoclonal Antibody
MBS8510428-01mLAF610	MyBiosource	0.1mL(AF610)	EUR 465

beta-Catenin Mouse Monoclonal Antibody
MBS8510428-01mLAF635	MyBiosource	0.1mL(AF635)	EUR 465

beta-Catenin Mouse Monoclonal Antibody
MBS9400133-01mL	MyBiosource	0.1mL	EUR 305

beta-Catenin Mouse Monoclonal Antibody
MBS9400133-5x01mL	MyBiosource	5x0.1mL	EUR 1230

beta-tubulin Mouse Monoclonal Antibody
MBS9400159-01mL	MyBiosource	0.1mL	EUR 305

beta-tubulin Mouse Monoclonal Antibody
MBS9400159-5x01mL	MyBiosource	5x0.1mL	EUR 1230

beta-tubulin Mouse Monoclonal Antibody
MBS9400441-01mL	MyBiosource	0.1mL	EUR 305

beta-tubulin Mouse Monoclonal Antibody
MBS9400441-5x01mL	MyBiosource	5x0.1mL	EUR 1230

Mouse monoclonal hCG beta antibody
MBS5306265-1mg	MyBiosource	1mg	EUR 465

Mouse monoclonal hCG beta antibody
MBS5306265-5x1mg	MyBiosource	5x1mg	EUR 1940

Mouse monoclonal hCG beta antibody
MBS5306266-01mg	MyBiosource	0.1mg	EUR 975

Mouse monoclonal hCG beta antibody
MBS5306266-5x01mg	MyBiosource	5x0.1mg	EUR 4245

Mouse monoclonal hCG beta antibody
MBS5306267-1mg	MyBiosource	1mg	EUR 185

Mouse monoclonal hCG beta antibody
MBS5306267-5x1mg	MyBiosource	5x1mg	EUR 685

Mouse monoclonal hCG beta antibody
MBS5306268-1mg	MyBiosource	1mg	EUR 185

Mouse monoclonal hCG beta antibody
MBS5306268-5x1mg	MyBiosource	5x1mg	EUR 690

TGF beta 1 Mouse Monoclonal Antibody
E10G20394	EnoGene	100 μl	EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

TGF beta 1 Mouse Monoclonal Antibody
E10G20396	EnoGene	100 μl	EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

TGF beta 1 Mouse Monoclonal Antibody
E10G20451	EnoGene	100 μl	EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

TGF beta R1, Monoclonal Antibody, Mouse
MBS555080-01mL	MyBiosource	0.1mL	EUR 380

TGF beta R1, Monoclonal Antibody, Mouse
MBS555080-5x01mL	MyBiosource	5x0.1mL	EUR 1560

Mouse monoclonal S100 beta antibody
MBS5307285-01mg	MyBiosource	0.1mg	EUR 975

Mouse monoclonal S100 beta antibody
MBS5307285-5x01mg	MyBiosource	5x0.1mg	EUR 4245

AMPK beta 1 Mouse Monoclonal Antibody
E10G20589	EnoGene	100 μl	EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

AMPK beta 1 Mouse Monoclonal Antibody
E10G20695	EnoGene	100 μl	EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

Mouse monoclonal beta Actin antibody
MBS5305245-01mL	MyBiosource	0.1mL	EUR 810

Mouse monoclonal beta Actin antibody
MBS5305245-5x01mL	MyBiosource	5x0.1mL	EUR 3505

Mouse monoclonal beta Actin antibody
MBS5305246-005mL	MyBiosource	0.05mL	EUR 280

Mouse monoclonal beta Actin antibody
MBS5305246-5x05mL	MyBiosource	5x0.5mL	EUR 1110

Mouse monoclonal Beta actin antibody
MBS5305247-005mg	MyBiosource	0.05mg	EUR 260

Mouse monoclonal Beta actin antibody
MBS5305247-5x005mg	MyBiosource	5x0.05mg	EUR 1025

Mouse Monoclonal beta Actin Antibody
TA346893	Origene Technologies GmbH	100 µl	Ask for price

Mouse Monoclonal beta Actin Antibody
TA346894	Origene Technologies GmbH	100 µl	Ask for price

beta Actin Mouse Monoclonal Antibody (1C7)
A01015-005ml	Abbkine	0.05ml	EUR 216
Description: A monoclonal antibody for detection of beta Actin from Human, Mouse, Rat, Monkey, Dog, Chicken, Rabbit, Hamster, Insect. This beta Actin antibody is for WB. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogen and conjugated to HRP. The antibody is produced in mouse by using as an immunogen synthetic peptide

beta Actin Mouse Monoclonal Antibody (1C7)
A01015-02ml	Abbkine	0.2ml	EUR 477.6
Description: A monoclonal antibody for detection of beta Actin from Human, Mouse, Rat, Monkey, Dog, Chicken, Rabbit, Hamster, Insect. This beta Actin antibody is for WB. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogen and conjugated to HRP. The antibody is produced in mouse by using as an immunogen synthetic peptide

beta Actin Mouse Monoclonal Antibody (1C7)
A01015-02ml5	Abbkine	0.2ml×5	EUR 1518
Description: A monoclonal antibody for detection of beta Actin from Human, Mouse, Rat, Monkey, Dog, Chicken, Rabbit, Hamster, Insect. This beta Actin antibody is for WB. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogen and conjugated to HRP. The antibody is produced in mouse by using as an immunogen synthetic peptide

Mouse monoclonal beta Tubulin antibody
MBS5305256-01mg	MyBiosource	0.1mg	EUR 360

Mouse monoclonal beta Tubulin antibody
MBS5305256-5x01mg	MyBiosource	5x0.1mg	EUR 1480

Mouse monoclonal beta Tubulin antibody
MBS5305257-01mg	MyBiosource	0.1mg	EUR 975

Mouse monoclonal beta Tubulin antibody
MBS5305257-5x01mg	MyBiosource	5x0.1mg	EUR 4245

Mouse monoclonal Beta tubulin antibody
MBS5305258-01mg	MyBiosource	0.1mg	EUR 670

Mouse monoclonal Beta tubulin antibody
MBS5305258-5x01mg	MyBiosource	5x0.1mg	EUR 2875

Mouse monoclonal Beta tubulin antibody
MBS5305259-01mg	MyBiosource	0.1mg	EUR 670

Mouse monoclonal Beta tubulin antibody
MBS5305259-5x01mg	MyBiosource	5x0.1mg	EUR 2875

Mouse Monoclonal beta Tubulin Antibody
TA347064	Origene Technologies GmbH	100 µl	Ask for price

Mouse Monoclonal beta Tubulin Antibody
TA347065	Origene Technologies GmbH	100 µl	Ask for price

beta I Tubulin Mouse Monoclonal Antibody
E10G20432	EnoGene	100 μl	EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

beta I Tubulin Mouse Monoclonal Antibody
E10G20440	EnoGene	100 μl	EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

Beta II tubulin mouse monoclonal antibody
MBS9611249-005mL	MyBiosource	0.05mL	EUR 260

Beta II tubulin mouse monoclonal antibody
MBS9611249-01mL	MyBiosource	0.1mL	EUR 325

Beta II tubulin mouse monoclonal antibody
MBS9611249-02mL	MyBiosource	0.2mL	EUR 400

Beta II tubulin mouse monoclonal antibody
MBS9611249-5x02mL	MyBiosource	5x0.2mL	EUR 1750

beta I tubulin Mouse Monoclonal Antibody
MBS8504338-01mg	MyBiosource	0.1mg	EUR 305

beta I tubulin Mouse Monoclonal Antibody
MBS8504338-01mLAF405L	MyBiosource	0.1mL(AF405L)	EUR 465

beta I tubulin Mouse Monoclonal Antibody
MBS8504338-01mLAF405S	MyBiosource	0.1mL(AF405S)	EUR 465

beta I tubulin Mouse Monoclonal Antibody
MBS8504338-01mLAF610	MyBiosource	0.1mL(AF610)	EUR 465

beta I tubulin Mouse Monoclonal Antibody
MBS8504338-01mLAF635	MyBiosource	0.1mL(AF635)	EUR 465

beta I tubulin Mouse Monoclonal Antibody
MBS8504950-01mg	MyBiosource	0.1mg	EUR 240

beta I tubulin Mouse Monoclonal Antibody
MBS8504950-01mLAF405L	MyBiosource	0.1mL(AF405L)	EUR 465

beta I tubulin Mouse Monoclonal Antibody
MBS8504950-01mLAF405S	MyBiosource	0.1mL(AF405S)	EUR 465

beta I tubulin Mouse Monoclonal Antibody
MBS8504950-01mLAF610	MyBiosource	0.1mL(AF610)	EUR 465

beta I tubulin Mouse Monoclonal Antibody
MBS8504950-01mLAF635	MyBiosource	0.1mL(AF635)	EUR 465

beta I tubulin Mouse Monoclonal Antibody
MBS9400106-01mL	MyBiosource	0.1mL	EUR 305

beta I tubulin Mouse Monoclonal Antibody
MBS9400106-5x01mL	MyBiosource	5x0.1mL	EUR 1230

Mouse Monoclonal Antibody to beta-Actin
sAP-0221	Angio Proteomie	50ug	EUR 270

Beta-Actin Mouse Monoclonal Antibody (1C7)
A01010-005ml	Cusabio	0.05ml	EUR 176.4
Description: A monoclonal antibody for detection of Beta-Actin from Human, Mouse, Rat, Monkey, Dog, Chicken, Rabbit, Insect, Hamster. This Beta-Actin antibody is for WB, IHC-P, IF. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide

Beta-Actin Mouse Monoclonal Antibody (1C7)
A01010-02ml	Abbkine	0.2ml	EUR 398.4
Description: A monoclonal antibody for detection of Beta-Actin from Human, Mouse, Rat, Monkey, Dog, Chicken, Rabbit, Insect, Hamster. This Beta-Actin antibody is for WB, IHC-P, IF. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide

Beta-Actin Mouse Monoclonal Antibody (1C7)
A01010-02ml5	Abbkine	0.2ml×5	EUR 1104
Description: A monoclonal antibody for detection of Beta-Actin from Human, Mouse, Rat, Monkey, Dog, Chicken, Rabbit, Insect, Hamster. This Beta-Actin antibody is for WB, IHC-P, IF. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide

Beta-Actin Mouse Monoclonal Antibody (1C7)
A01010A350-01ml	Abbkine	0.1ml	EUR 320.4
Description: A monoclonal antibody for detection of Beta-Actin from Human, Mouse, Rat, Monkey, Dog, Chicken, Rabbit, Insect, Hamster. This Beta-Actin antibody is for IHC-P, IF. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogen and conjugated to AbFluor? 350. The antibody is produced in mouse by using as an immunogen synthetic peptide

Beta-Actin Mouse Monoclonal Antibody (1C7)
A01010A405-01ml	Abbkine	0.1ml	EUR 320.4
Description: A monoclonal antibody for detection of Beta-Actin from Human, Mouse, Rat, Monkey, Dog, Chicken, Rabbit, Insect, Hamster. This Beta-Actin antibody is for IHC-P, IF. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogen and conjugated to AbFluor? 405. The antibody is produced in mouse by using as an immunogen synthetic peptide

Beta-Actin Mouse Monoclonal Antibody (1C7)
A01010A488-01ml	Abbkine	0.1ml	EUR 320.4
Description: A monoclonal antibody for detection of Beta-Actin from Human, Mouse, Rat, Monkey, Dog, Chicken, Rabbit, Insect, Hamster. This Beta-Actin antibody is for IHC-P, IF. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogen and conjugated to AbFluor? 488. The antibody is produced in mouse by using as an immunogen synthetic peptide

Variation of the provider peptide additionally shed some gentle on the dramatic influence of refined sequence variations on the corresponding ASO conjugate efficiency in vivo, an space which clearly warrant additional investigations. We now have confirmed the exceptional potential of GLP1R agonist conjugation for the supply of ASOs to pancreatic beta cell by successfully flattening islet amyloid polypeptide (IAPP) mRNA, a possible proapoptotic goal, in mice.