Design and Immunological Evaluation of a Hybrid Peptide as a Potent TLR2 Agonist by Structure-Based Virtual Screening

Design and Immunological Evaluation of a Hybrid Peptide as a Potent TLR2 Agonist by Structure-Based Virtual Screening

Design and Immunological Evaluation of a Hybrid Peptide as a Potent TLR2 Agonist by Structure-Based Virtual Screening

Immunity is a flexible defensive response that’s concerned in defending in opposition to illness by figuring out and destroying self and non-self dangerous substances. As a state of non permanent or everlasting immune dysfunction, immunosuppression could make an organism extra inclined to an infection, organ harm, and most cancers attributable to harm to the immune system. It has taken a very long time to develop new immunomodulatory brokers to forestall and deal with immunosuppressive ailments.

In recent times, Toll-like receptor 2 (TLR2) agonists have been reported to have profound results on the immune system, and they’re thought to be potent immunomodulatory candidates. TP5 and LL-37, the potent immunomodulatory brokers, have been reported to provide a sturdy innate immune response by binding to TLR2. Nevertheless, their growth has been weakened by a number of considerations, reminiscent of potential cytotoxicity, weak physiological stability and poor immunomodulatory exercise.

To beat these challenges, hybridization has been proposed. Due to this fact, six hybrid peptides (LTPa, LTPb, LTPc, TPLa, TPLb, and TPLc) had been designed by combining the full-length TP5 with a attribute fragment of LL-37 that included LL-37 (13-36), LL-37 (17-29), and LL-37 (13-31). LTPa, probably the most potent TLR2 agonist, was merely and successfully screened by molecular docking and in vitro experiments.

Moreover, the immunomodulatory results of LTPa had been confirmed by a CTX-immunosuppressed murine mannequin, which demonstrated that LTPa efficiently inhibit immunosuppression, elevated immune organ indices, enhanced DC maturation, regulated T lymphocyte subsets, and elevated cytokine and Ig contents. Our examine additionally revealed that the immunomodulatory results of LTPa are related to binding to TLR2, forming TLR2 clusters, and activating the NF-κB signaling pathway.

Immunostimulatory TLR7 agonist-nanoparticles along with checkpoint blockade for efficient most cancers immunotherapy

Mono- or dual-checkpoint inhibitors for immunotherapy have modified the paradigm of most cancers care; nevertheless, solely a minority of sufferers responds to such therapy. Combining small molecule immuno-stimulators can enhance therapy efficacy, however they’re restricted by poor pharmacokinetics. On this examine, TLR7 agonists conjugated onto silica nanoparticles confirmed prolonged drug localization after intratumoral injection. The nanoparticle-based TLR7 agonist elevated immune stimulation by activating the TLR7 signaling pathway.

When treating CT26 colon most cancers, nanoparticle conjugated TLR7 agonists elevated T cell infiltration into the tumors by > 4× and upregulated expression of the interferon γ gene in comparison with its unconjugated counterpart by ~2×. Toxicity assays established that the conjugated TLR7 agonist is a protected agent on the efficient dose.

When mixed with checkpoint inhibitors that concentrate on programmed cell demise protein 1 (PD-1) and cytotoxic T-lymphocyte-associated protein 4 (CTLA-4), a 10-100× enhance in immune cell migration was noticed; moreover, 100 mm3 tumors had been handled and a 60% remission price was noticed together with remission at contralateral non-injected tumors. The info present that nanoparticle primarily based TLR7 agonists are protected and might potentiate the effectiveness of checkpoint inhibitors in immunotherapy resistant tumor fashions and promote a long-term particular reminiscence immune operate.

Detrimental Impression of Sigma-1 Receptor Agonist Remedy on Tissue Integrity and Motor Perform Following Spinal Wire Damage

In traumatic spinal wire harm, the preliminary trauma is adopted by a cascade of impairments, together with excitotoxicity and calcium overload, which finally induces secondary damages. The sigma-1 receptor is extensively expressed within the central nervous system and is acknowledged to play a key function in calcium homeostasis. Remedies with agonists of the sigma-1 receptor induce useful results in a number of animal fashions of neurological ailments. In traumatic harm the usage of an antagonist of the sigma-1 receptor reversed a number of signs of central neuropathic ache.

Right here, we investigated whether or not sigma-1 receptor activation with PRE-084 is useful or detrimental following SCI in mice. First, we report that PRE-084 therapy after harm doesn’t enhance motor operate restoration. Second, utilizing ex vivo diffusion weighted magnetic resonance imaging accomplished by histological evaluation, we spotlight that σ1R agonist therapy after SCI doesn’t restrict lesion measurement.

Design and Immunological Evaluation of a Hybrid Peptide as a Potent TLR2 Agonist by Structure-Based Virtual Screening

Lastly, PRE-084 therapy following SCI decreases NeuN expression and will increase astrocytic reactivity. Our findings recommend that activation of sigma-1 receptor after traumatic spinal wire harm is detrimental on tissue preservation and motor operate restoration in mice.

Protecting Impact of Adenosine A 2B Receptor Agonist, BAY60-6583, In opposition to Transient Focal Mind Ischemia in Rat

Cerebral ischemia is a multifactorial pathology characterised first by an acute harm, attributable to excitotoxicity, adopted by a secondary mind harm that develops hours to days after ischemia. Throughout ischemia, adenosine acts as an endogenous neuroprotectant. Few research have investigated the function of A2B receptor in mind ischemia due to the low efficiency of adenosine for it and the few selective ligands developed up to now.

A2B receptors are scarcely however extensively distributed within the mind on neurons, glial and endothelial cells and on hematopoietic cells, lymphocytes and neutrophils, the place they exert primarily anti-inflammatory results, inhibiting vascular adhesion and inflammatory cells migration. Intention of this work was to confirm whether or not continual administration of the A2B agonist, BAY60-6583 (0.1 mg/kg i.p., twice/day), beginning Four h after focal ischemia induced by transient (1 h) Center Cerebral Artery occlusion (tMCAo) within the rat, was protecting after the ischemic insult.

BAY60-6583 improved the neurological deficit as much as 7 days after tMCAo. Seven days after ischemia BAY60-6583 diminished considerably the ischemic mind harm in cortex and striatum, counteracted ischemia-induced neuronal demise, diminished microglia activation and astrocytes alteration. Furthermore, it decreased the expression of TNF-α and elevated that of IL-10 in peripheral plasma.

THR-β agonist 4

T63515-1mg 1mg Ask for price
Description: THR-β agonist 4

THR-β agonist 4

T63515-50mg 50mg Ask for price
Description: THR-β agonist 4

THR-β agonist 4

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Description: THR-β agonist 4

THR-β agonist 3

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Description: THR-β agonist 3

THR-β agonist 3

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Description: THR-β agonist 3

THR-β agonist 3

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Description: THR-β agonist 3

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Description: THR-β agonist 3

THR-β agonist 1

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Description: THR-β agonist 1

THR-β agonist 1

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Description: THR-β agonist 1

THR-β agonist 1

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Description: THR-β agonist 1

THR-β agonist 1

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Description: THR-β agonist 1

THR-β agonist 1

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Description: THR-β agonist 1

THR-β agonist 2

T62594-10mg 10mg Ask for price
Description: THR-β agonist 2

THR-β agonist 2

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Description: THR-β agonist 2

THR-β agonist 2

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Description: THR-β agonist 2

THR-β agonist 2

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Description: THR-β agonist 2

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Description: THR-β agonist 2

THR-β agonist 5

T61759-10mg 10mg Ask for price
Description: THR-β agonist 5

THR-β agonist 5

T61759-1g 1g Ask for price
Description: THR-β agonist 5

THR-β agonist 5

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Description: THR-β agonist 5

THR-β agonist 5

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Description: THR-β agonist 5

THR-β agonist 5

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Description: THR-β agonist 5

Wnt/β-catenin agonist 2

T41094-10mg 10mg Ask for price
Description: Wnt/β-catenin agonist 2

Wnt/β-catenin agonist 2

T41094-1g 1g Ask for price
Description: Wnt/β-catenin agonist 2

Wnt/β-catenin agonist 2

T41094-1mg 1mg Ask for price
Description: Wnt/β-catenin agonist 2

Wnt/β-catenin agonist 2

T41094-50mg 50mg Ask for price
Description: Wnt/β-catenin agonist 2

Wnt/β-catenin agonist 2

T41094-5mg 5mg Ask for price
Description: Wnt/β-catenin agonist 2

Wnt/β-catenin agonist 4

T60803-10mg 10mg Ask for price
Description: Wnt/β-catenin agonist 4

Wnt/β-catenin agonist 4

T60803-1g 1g Ask for price
Description: Wnt/β-catenin agonist 4

Wnt/β-catenin agonist 4

T60803-1mg 1mg Ask for price
Description: Wnt/β-catenin agonist 4

Wnt/β-catenin agonist 4

T60803-50mg 50mg Ask for price
Description: Wnt/β-catenin agonist 4

Wnt/β-catenin agonist 4

T60803-5mg 5mg Ask for price
Description: Wnt/β-catenin agonist 4

Wnt/β-catenin agonist 1

T13344-10mg 10mg Ask for price
Description: Wnt/β-catenin agonist 1

Wnt/β-catenin agonist 1

T13344-1g 1g Ask for price
Description: Wnt/β-catenin agonist 1

Wnt/β-catenin agonist 1

T13344-1mg 1mg Ask for price
Description: Wnt/β-catenin agonist 1

Wnt/β-catenin agonist 1

T13344-50mg 50mg Ask for price
Description: Wnt/β-catenin agonist 1

Wnt/β-catenin agonist 1

T13344-5mg 5mg Ask for price
Description: Wnt/β-catenin agonist 1

β cell proliferation agonist WS3

HY-12462 10mM/1mL
EUR 195.6

Bid ELISA Kit| Mouse BH3 Interacting Domain Death Agonist ELISA

EF013466 96 Tests
EUR 826.8

Rat BH3 Interacting Domain Death Agonist ELISA kit

E01A10462 96T
EUR 700
Description: ELISA

Dog BH3 Interacting Domain Death Agonist ELISA kit

E08B0306-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Canine BH3 Interacting Domain Death Agonist in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog BH3 Interacting Domain Death Agonist ELISA kit

E08B0306-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Canine BH3 Interacting Domain Death Agonist in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog BH3 Interacting Domain Death Agonist ELISA kit

E08B0306-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Canine BH3 Interacting Domain Death Agonist in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig BH3 Interacting Domain Death Agonist ELISA kit

E07B0306-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Porcine BH3 Interacting Domain Death Agonist in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig BH3 Interacting Domain Death Agonist ELISA kit

E07B0306-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Porcine BH3 Interacting Domain Death Agonist in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig BH3 Interacting Domain Death Agonist ELISA kit

E07B0306-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Porcine BH3 Interacting Domain Death Agonist in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat BH3 Interacting Domain Death Agonist ELISA kit

E02B0306-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rat BH3 Interacting Domain Death Agonist in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat BH3 Interacting Domain Death Agonist ELISA kit

E02B0306-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rat BH3 Interacting Domain Death Agonist in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat BH3 Interacting Domain Death Agonist ELISA kit

E02B0306-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rat BH3 Interacting Domain Death Agonist in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat BH3 Interacting Domain Death Agonist ELISA Kit

IRTBIDKT each
EUR 718
Description: Rat BH3 Interacting Domain Death Agonist ELISA Kit

Goat BH3 Interacting Domain Death Agonist ELISA kit

E01A45374 96T
EUR 700
Description: ELISA

Goat BH3 Interacting Domain Death Agonist ELISA kit

E06B0306-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Goat BH3 Interacting Domain Death Agonist in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat BH3 Interacting Domain Death Agonist ELISA kit

E06B0306-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Goat BH3 Interacting Domain Death Agonist in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat BH3 Interacting Domain Death Agonist ELISA kit

E06B0306-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Goat BH3 Interacting Domain Death Agonist in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Bid ELISA Kit| Rat BH3-interacting domain death agonist ELISA Ki

EF017208 96 Tests
EUR 826.8

Sheep BH3 Interacting Domain Death Agonist ELISA kit

E01A97667 96T
EUR 700
Description: ELISA

Mouse BH3 Interacting Domain Death Agonist ELISA kit

E03B0306-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Mouse BH3 Interacting Domain Death Agonist in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse BH3 Interacting Domain Death Agonist ELISA kit

E03B0306-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Mouse BH3 Interacting Domain Death Agonist in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse BH3 Interacting Domain Death Agonist ELISA kit

E03B0306-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Mouse BH3 Interacting Domain Death Agonist in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human BH3 Interacting Domain Death Agonist ELISA kit

E01B0306-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Human BH3 Interacting Domain Death Agonist in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human BH3 Interacting Domain Death Agonist ELISA kit

E01B0306-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Human BH3 Interacting Domain Death Agonist in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human BH3 Interacting Domain Death Agonist ELISA kit

E01B0306-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Human BH3 Interacting Domain Death Agonist in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human BH3 Interacting Domain Death Agonist ELISA kit

E01A1700 96T
EUR 700
Description: ELISA

Mouse BH3 Interacting Domain Death Agonist ELISA kit

E01A19203 96T
EUR 700
Description: ELISA

BH3-Interacting Domain Death Agonist (BID) ELISA Kit

abx595062-96tests 96 tests
EUR 764.4

Human BH3 Interacting Domain Death Agonist ELISA Kit

IHUBIDKT each
EUR 667
Description: Human BH3 Interacting Domain Death Agonist ELISA Kit

Mouse BH3 Interacting Domain Death Agonist ELISA Kit

IMSBIDKT each
EUR 616
Description: Mouse BH3 Interacting Domain Death Agonist ELISA Kit

Rat BH3 Interacting Domain Death Agonist (Bid) ELISA Kit

DLR-Bid-Ra 96T
EUR 454
Description: serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rat BH3 Interacting Domain Death Agonist (Bid) ELISA Kit

DLR-Bid-Ra-48T 48T
EUR 609.6
Description: A sandwich quantitative ELISA assay kit for detection of Rat BH3 Interacting Domain Death Agonist (Bid) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rat BH3 Interacting Domain Death Agonist (Bid) ELISA Kit

DLR-Bid-Ra-96T 96T
EUR 793.2
Description: A sandwich quantitative ELISA assay kit for detection of Rat BH3 Interacting Domain Death Agonist (Bid) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rat Bid(BH3 Interacting Domain Death Agonist) ELISA Kit

ELK1704-48T 48T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat Bid. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat Bid. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Rat Bid, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Rat Bid in the samples is then determined by comparing the OD of the samples to the standard curve.

Rat Bid(BH3 Interacting Domain Death Agonist) ELISA Kit

ELK1704-96T 96T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat Bid. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat Bid. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Rat Bid, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Rat Bid in the samples is then determined by comparing the OD of the samples to the standard curve.

Rat BH3 Interacting Domain Death Agonist (Bid) ELISA Kit

EKN43828-48T 48T
EUR 370.02

Rat BH3 Interacting Domain Death Agonist (Bid) ELISA Kit

EKN43828-5x96T 5x96T
EUR 2510.85

Rat BH3 Interacting Domain Death Agonist (Bid) ELISA Kit

EKN43828-96T 96T
EUR 528.6

Rat BH3 Interacting Domain Death Agonist (Bid) ELISA Kit

EKU02717-48T 48T
EUR 542.78

Rat BH3 Interacting Domain Death Agonist (Bid) ELISA Kit

EKU02717-5x96T 5x96T
EUR 3683.15

Rat BH3 Interacting Domain Death Agonist (Bid) ELISA Kit

EKU02717-96T 96T
EUR 775.4

Rat BH3 interacting domain death agonist(Bid)ELISA Kit

GA-E0045RT-48T 48T
EUR 380.4

Rat BH3 interacting domain death agonist(Bid)ELISA Kit

GA-E0045RT-96T 96T
EUR 595.2

Rat BH3 Interacting Domain Death Agonist (Bid) ELISA Kit

DL-Bid-Ra 96T
EUR 432
Description: serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rat BH3 Interacting Domain Death Agonist (Bid) ELISA Kit

EK12860 96Т
EUR 768

Rat BH3 Interacting Domain Death Agonist (BID) ELISA Kit

abx572028-96tests 96 tests
EUR 848.4

Pig BH3 Interacting Domain Death Agonist (BID) ELISA Kit

abx360959-96tests 96 tests
EUR 990

Rat BH3 interacting domain death agonist,Bid ELISA Kit

CN-01707R1 96T
EUR 556.8

Rat BH3 interacting domain death agonist,Bid ELISA Kit

CN-01707R2 48T
EUR 375.6

Rat BH3 Interacting Domain Death Agonist (BID) ELISA Kit

abx256314-96tests 96 tests
EUR 848.4

Rat BH3 Interacting Domain Death Agonist (Bid) ELISA Kit

20-abx155258
  • Ask for price
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  • Ask for price
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Rat BH3 Interacting Domain Death Agonist (Bid) ELISA Kit

RDR-Bid-Ra-48T 48T
EUR 465.47
Description: serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.

Rat BH3 Interacting Domain Death Agonist (Bid) ELISA Kit

RDR-Bid-Ra-48Tests 48 Tests
EUR 640.8

Rat BH3 Interacting Domain Death Agonist (Bid) ELISA Kit

RDR-Bid-Ra-96T 96T
EUR 664.97
Description: serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.

Rat BH3 Interacting Domain Death Agonist (Bid) ELISA Kit

RDR-Bid-Ra-96Tests 96 Tests
EUR 890.4

Rat BH3 Interacting Domain Death Agonist (Bid) ELISA Kit

RD-Bid-Ra-48T 48T
EUR 443.3
Description: serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.

Rat BH3 Interacting Domain Death Agonist (Bid) ELISA Kit

RD-Bid-Ra-48Tests 48 Tests
EUR 613.2

Rat BH3 Interacting Domain Death Agonist (Bid) ELISA Kit

RD-Bid-Ra-96T 96T
EUR 633.3
Description: serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.

Rat BH3 Interacting Domain Death Agonist (Bid) ELISA Kit

RD-Bid-Ra-96Tests 96 Tests
EUR 850.8

Rat BH3 interacting domain death agonist (BID) ELISA Kit

RK07088 96T
EUR 280

Rat BH3 interacting domain death agonist(Bid)ELISA Kit

QY-E11608 96T
EUR 433.2

Rat BH3 Interacting Domain Death Agonist(Bid) ELISA Kit

NSL0732r 96 Tests
EUR 498

ELISA Kit for BH3 Interacting Domain Death Agonist (Bid)

SEA629Hu 96Т
EUR 630

ELISA Kit for BH3 Interacting Domain Death Agonist (Bid)

SEA629Mu 96Т
EUR 576

ELISA Kit for BH3 Interacting Domain Death Agonist (Bid)

SEA629Ra 96Т
EUR 684

Rat BH3 Interacting Domain Death Agonist (Bid) ELISA Kit

SEA629Ra-10x96wellstestplate 10x96-wells test plate
EUR 5552.14
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat BH3 Interacting Domain Death Agonist (Bid) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Rat BH3 Interacting Domain Death Agonist (Bid) ELISA Kit

SEA629Ra-1x48wellstestplate 1x48-wells test plate
EUR 562.42
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat BH3 Interacting Domain Death Agonist (Bid) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Rat BH3 Interacting Domain Death Agonist (Bid) ELISA Kit

SEA629Ra-1x96wellstestplate 1x96-wells test plate
EUR 752.02
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat BH3 Interacting Domain Death Agonist (Bid) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Rat BH3 Interacting Domain Death Agonist (Bid) ELISA Kit

SEA629Ra-5x96wellstestplate 5x96-wells test plate
EUR 3024.07
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat BH3 Interacting Domain Death Agonist (Bid) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Rat BH3 Interacting Domain Death Agonist (Bid) ELISA Kit

4-SEA629Ra
  • Ask for price
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  • Ask for price
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Rat BH3 Interacting Domain Death Agonist (Bid) in samples from Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species.

Rat BH3 interacting domain death agonist,Bid ELISA Kit

SL0115Ra -
EUR 498

Rat BH3 interacting domain death agonist,Bid ELISA Kit

YLA0610RA-48T 48T Ask for price

Rat BH3 interacting domain death agonist,Bid ELISA Kit

YLA0610RA-96T 96T Ask for price

Rat BH3 Interacting Domain Death Agonist (BID) ELISA Kit

abx256314-1096tests 10 × 96 tests Ask for price

Rat BH3 Interacting Domain Death Agonist (BID) ELISA Kit

abx256314-596tests 5 × 96 tests Ask for price

Rat BH3 Interacting Domain Death Agonist (Bid) ELISA Kit

abx155258-100l 100 µl
EUR 675

Pig BH3 Interacting Domain Death Agonist (BID) ELISA Kit

abx360959-100g 100 µg
EUR 687.5

Canine BH3 Interacting Domain Death Agonist ELISA kit

E01A62808 96T
EUR 700
Description: ELISA

Rabbit BH3 Interacting Domain Death Agonist ELISA kit

E01A27942 96T
EUR 700
Description: ELISA

Rabbit BH3 Interacting Domain Death Agonist ELISA kit

E04B0306-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rabbit BH3 Interacting Domain Death Agonist in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit BH3 Interacting Domain Death Agonist ELISA kit

E04B0306-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rabbit BH3 Interacting Domain Death Agonist in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit BH3 Interacting Domain Death Agonist ELISA kit

E04B0306-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rabbit BH3 Interacting Domain Death Agonist in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey BH3 Interacting Domain Death Agonist ELISA kit

E01A71521 96T
EUR 700
Description: ELISA

Bovine BH3 Interacting Domain Death Agonist ELISA kit

E01A80238 96T
EUR 700
Description: ELISA

Monkey BH3 Interacting Domain Death Agonist ELISA kit

E09B0306-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Monkey BH3 Interacting Domain Death Agonist in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey BH3 Interacting Domain Death Agonist ELISA kit

E09B0306-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Monkey BH3 Interacting Domain Death Agonist in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey BH3 Interacting Domain Death Agonist ELISA kit

E09B0306-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Monkey BH3 Interacting Domain Death Agonist in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat BH3 Interacting Domain Death Agonist(Bid) ELISA Kit

NSL0997Gt 96T
EUR 528

Porcine BH3 Interacting Domain Death Agonist ELISA kit

E01A54091 96T
EUR 700
Description: ELISA

Chicken BH3 Interacting Domain Death Agonist ELISA kit

E01A88964 96T
EUR 700
Description: ELISA

Human BH3 interacting domain death agonist,Bid ELISA Kit

201-12-1832 96 tests
EUR 528
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human BH3 Interacting Domain Death Agonist (Bid) ELISA Kit

DLR-Bid-Hu 96T
EUR 422
Description: serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human BH3 Interacting Domain Death Agonist (Bid) ELISA Kit

DLR-Bid-Hu-48T 48T
EUR 574.8
Description: A sandwich quantitative ELISA assay kit for detection of Human BH3 Interacting Domain Death Agonist (Bid) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human BH3 Interacting Domain Death Agonist (Bid) ELISA Kit

DLR-Bid-Hu-96T 96T
EUR 745.2
Description: A sandwich quantitative ELISA assay kit for detection of Human BH3 Interacting Domain Death Agonist (Bid) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Mouse BH3 Interacting Domain Death Agonist (Bid) ELISA Kit

DLR-Bid-Mu 96T
EUR 389
Description: serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Mouse BH3 Interacting Domain Death Agonist (Bid) ELISA Kit

DLR-Bid-Mu-48T 48T
EUR 540
Description: A sandwich quantitative ELISA assay kit for detection of Mouse BH3 Interacting Domain Death Agonist (Bid) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Mouse BH3 Interacting Domain Death Agonist (Bid) ELISA Kit

DLR-Bid-Mu-96T 96T
EUR 698.4
Description: A sandwich quantitative ELISA assay kit for detection of Mouse BH3 Interacting Domain Death Agonist (Bid) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rat Bid/ BH3-interacting domain death agonist ELISA Kit

E0127Ra 1 Kit
EUR 557
Description: p22 BID,BID

Mouse Bid(BH3 Interacting Domain Death Agonist) ELISA Kit

EM0871 96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA ;Reacts with: Mus ;Sensitivity: 0.188 ng/ml

Rat Bid(BH3-interacting domain death agonist) ELISA Kit

ER0336 96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Rattus;Sensitivity: 0.188 ng/ml

Mouse Bid(BH3 Interacting Domain Death Agonist) ELISA Kit

ELK1067-48T 48T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse Bid. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse Bid. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Mouse Bid, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Mouse Bid in the samples is then determined by comparing the OD of the samples to the standard curve.

Mouse Bid(BH3 Interacting Domain Death Agonist) ELISA Kit

ELK1067-96T 96T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse Bid. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse Bid. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Mouse Bid, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Mouse Bid in the samples is then determined by comparing the OD of the samples to the standard curve.

Human Bid(BH3 Interacting Domain Death Agonist) ELISA Kit

ELK1703-48T 48T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human Bid. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human Bid. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Human Bid, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human Bid in the samples is then determined by comparing the OD of the samples to the standard curve.

Human Bid(BH3 Interacting Domain Death Agonist) ELISA Kit

ELK1703-96T 96T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human Bid. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human Bid. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Human Bid, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human Bid in the samples is then determined by comparing the OD of the samples to the standard curve.

Human BH3 interacting domain death agonist(Bid) Elisa Kit

EK714819 96 Wells
EUR 0.49

Human BH3 Interacting Domain Death Agonist (Bid) ELISA Kit

EKN43826-48T 48T
EUR 341.04

Human BH3 Interacting Domain Death Agonist (Bid) ELISA Kit

EKN43826-5x96T 5x96T
EUR 2314.2

Human BH3 Interacting Domain Death Agonist (Bid) ELISA Kit

EKN43826-96T 96T
EUR 487.2

Mouse BH3 Interacting Domain Death Agonist (Bid) ELISA Kit

EKN43827-48T 48T
EUR 311.22

Mouse BH3 Interacting Domain Death Agonist (Bid) ELISA Kit

EKN43827-5x96T 5x96T
EUR 2111.85

Mouse BH3 Interacting Domain Death Agonist (Bid) ELISA Kit

EKN43827-96T 96T
EUR 444.6

Human BH3- interacting domain death agonist, BID ELISA KIT

ELI-02236h 96 Tests
EUR 988.8

Mouse BH3- interacting domain death agonist, Bid ELISA KIT

ELI-02238m 96 Tests
EUR 1038

Human BH3 Interacting Domain Death Agonist (Bid) ELISA Kit

EKL55817-5x96T 5x96T
EUR 3452.78

Human BH3 Interacting Domain Death Agonist (Bid) ELISA Kit

EKL55817-96T 96T
EUR 726.9

Human BID (BH3 Interacting Domain Death Agonist) ELISA Kit

EKE60395-5x96T 5x96T
EUR 3124.08

Human BID (BH3 Interacting Domain Death Agonist) ELISA Kit

EKE60395-96T 96T
EUR 657.7

Human BH3 Interacting Domain Death Agonist (Bid) ELISA Kit

EKU02715-48T 48T
EUR 500.5

Human BH3 Interacting Domain Death Agonist (Bid) ELISA Kit

EKU02715-5x96T 5x96T
EUR 3396.25

Human BH3 Interacting Domain Death Agonist (Bid) ELISA Kit

EKU02715-96T 96T
EUR 715

Mouse BH3 Interacting Domain Death Agonist (Bid) ELISA Kit

EKU02716-48T 48T
EUR 457.38

Mouse BH3 Interacting Domain Death Agonist (Bid) ELISA Kit

EKU02716-5x96T 5x96T
EUR 3103.65

Mouse BH3 Interacting Domain Death Agonist (Bid) ELISA Kit

EKU02716-96T 96T
EUR 653.4

Human BH3 interacting domain death agonist(Bid)ELISA Kit

GA-E1848HM-48T 48T
EUR 346.8

Human BH3 interacting domain death agonist(Bid)ELISA Kit

GA-E1848HM-96T 96T
EUR 559.2

Mouse BH3 interacting domain death agonist(Bid)ELISA Kit

GA-E0639MS-48T 48T
EUR 403.2

Mouse BH3 interacting domain death agonist(Bid)ELISA Kit

GA-E0639MS-96T 96T
EUR 640.8

Human BH3 Interacting Domain Death Agonist (Bid) ELISA Kit

DL-Bid-Hu 96T
EUR 402
Description: serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Two days after ischemia BAY60-6583 diminished blood cell infiltration within the ischemic cortex. The current examine signifies that A2B receptors stimulation can attenuate the neuroinflammation that develops after ischemia, suggesting that A2B receptors could characterize a brand new attention-grabbing pharmacological goal to guard from degeneration after mind ischemia.

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