Design and Immunological Evaluation of a Hybrid Peptide as a Potent TLR2 Agonist by Structure-Based Virtual Screening

Design and Immunological Evaluation of a Hybrid Peptide as a Potent TLR2 Agonist by Structure-Based Virtual Screening

Design and Immunological Evaluation of a Hybrid Peptide as a Potent TLR2 Agonist by Structure-Based Virtual Screening

Immunity is a flexible defensive response that’s concerned in defending in opposition to illness by figuring out and destroying self and non-self dangerous substances. As a state of non permanent or everlasting immune dysfunction, immunosuppression could make an organism extra inclined to an infection, organ harm, and most cancers attributable to harm to the immune system. It has taken a very long time to develop new immunomodulatory brokers to forestall and deal with immunosuppressive ailments.

In recent times, Toll-like receptor 2 (TLR2) agonists have been reported to have profound results on the immune system, and they’re thought to be potent immunomodulatory candidates. TP5 and LL-37, the potent immunomodulatory brokers, have been reported to provide a sturdy innate immune response by binding to TLR2. Nevertheless, their growth has been weakened by a number of considerations, reminiscent of potential cytotoxicity, weak physiological stability and poor immunomodulatory exercise.

To beat these challenges, hybridization has been proposed. Due to this fact, six hybrid peptides (LTPa, LTPb, LTPc, TPLa, TPLb, and TPLc) had been designed by combining the full-length TP5 with a attribute fragment of LL-37 that included LL-37 (13-36), LL-37 (17-29), and LL-37 (13-31). LTPa, probably the most potent TLR2 agonist, was merely and successfully screened by molecular docking and in vitro experiments.

Moreover, the immunomodulatory results of LTPa had been confirmed by a CTX-immunosuppressed murine mannequin, which demonstrated that LTPa efficiently inhibit immunosuppression, elevated immune organ indices, enhanced DC maturation, regulated T lymphocyte subsets, and elevated cytokine and Ig contents. Our examine additionally revealed that the immunomodulatory results of LTPa are related to binding to TLR2, forming TLR2 clusters, and activating the NF-κB signaling pathway.

Immunostimulatory TLR7 agonist-nanoparticles along with checkpoint blockade for efficient most cancers immunotherapy

Mono- or dual-checkpoint inhibitors for immunotherapy have modified the paradigm of most cancers care; nevertheless, solely a minority of sufferers responds to such therapy. Combining small molecule immuno-stimulators can enhance therapy efficacy, however they’re restricted by poor pharmacokinetics. On this examine, TLR7 agonists conjugated onto silica nanoparticles confirmed prolonged drug localization after intratumoral injection. The nanoparticle-based TLR7 agonist elevated immune stimulation by activating the TLR7 signaling pathway.

When treating CT26 colon most cancers, nanoparticle conjugated TLR7 agonists elevated T cell infiltration into the tumors by > 4× and upregulated expression of the interferon γ gene in comparison with its unconjugated counterpart by ~2×. Toxicity assays established that the conjugated TLR7 agonist is a protected agent on the efficient dose.

When mixed with checkpoint inhibitors that concentrate on programmed cell demise protein 1 (PD-1) and cytotoxic T-lymphocyte-associated protein 4 (CTLA-4), a 10-100× enhance in immune cell migration was noticed; moreover, 100 mm3 tumors had been handled and a 60% remission price was noticed together with remission at contralateral non-injected tumors. The info present that nanoparticle primarily based TLR7 agonists are protected and might potentiate the effectiveness of checkpoint inhibitors in immunotherapy resistant tumor fashions and promote a long-term particular reminiscence immune operate.

Detrimental Impression of Sigma-1 Receptor Agonist Remedy on Tissue Integrity and Motor Perform Following Spinal Wire Damage

In traumatic spinal wire harm, the preliminary trauma is adopted by a cascade of impairments, together with excitotoxicity and calcium overload, which finally induces secondary damages. The sigma-1 receptor is extensively expressed within the central nervous system and is acknowledged to play a key function in calcium homeostasis. Remedies with agonists of the sigma-1 receptor induce useful results in a number of animal fashions of neurological ailments. In traumatic harm the usage of an antagonist of the sigma-1 receptor reversed a number of signs of central neuropathic ache.

Right here, we investigated whether or not sigma-1 receptor activation with PRE-084 is useful or detrimental following SCI in mice. First, we report that PRE-084 therapy after harm doesn’t enhance motor operate restoration. Second, utilizing ex vivo diffusion weighted magnetic resonance imaging accomplished by histological evaluation, we spotlight that σ1R agonist therapy after SCI doesn’t restrict lesion measurement.

Design and Immunological Evaluation of a Hybrid Peptide as a Potent TLR2 Agonist by Structure-Based Virtual Screening

Lastly, PRE-084 therapy following SCI decreases NeuN expression and will increase astrocytic reactivity. Our findings recommend that activation of sigma-1 receptor after traumatic spinal wire harm is detrimental on tissue preservation and motor operate restoration in mice.

Protecting Impact of Adenosine A 2B Receptor Agonist, BAY60-6583, In opposition to Transient Focal Mind Ischemia in Rat

Cerebral ischemia is a multifactorial pathology characterised first by an acute harm, attributable to excitotoxicity, adopted by a secondary mind harm that develops hours to days after ischemia. Throughout ischemia, adenosine acts as an endogenous neuroprotectant. Few research have investigated the function of A2B receptor in mind ischemia due to the low efficiency of adenosine for it and the few selective ligands developed up to now.

A2B receptors are scarcely however extensively distributed within the mind on neurons, glial and endothelial cells and on hematopoietic cells, lymphocytes and neutrophils, the place they exert primarily anti-inflammatory results, inhibiting vascular adhesion and inflammatory cells migration. Intention of this work was to confirm whether or not continual administration of the A2B agonist, BAY60-6583 (0.1 mg/kg i.p., twice/day), beginning Four h after focal ischemia induced by transient (1 h) Center Cerebral Artery occlusion (tMCAo) within the rat, was protecting after the ischemic insult.

BAY60-6583 improved the neurological deficit as much as 7 days after tMCAo. Seven days after ischemia BAY60-6583 diminished considerably the ischemic mind harm in cortex and striatum, counteracted ischemia-induced neuronal demise, diminished microglia activation and astrocytes alteration. Furthermore, it decreased the expression of TNF-α and elevated that of IL-10 in peripheral plasma.

β- agonists
AT166 1mg
EUR 1134

ẞ-Agonists ELISA Kit
ELKFS047 96Tests
EUR 175

Beta- agonists
AG166 1 mg
EUR 627.6

β-agonist ELISA kit
LSY-10036 96 well/kit Ask for price

beta-agonist (β-agonist) ELISA Kit
RDF-E078 96T
EUR 480

THR-β agonist 5
HY-147055 1 mg
EUR 1623.4
Description: THR-β agonist 5 (compound 54) is a potent THR-β agonist, with an EC50 of <50 nM[1].

THR-β agonist 6
HY-149218 Get quote Ask for price
Description: THR-β agonist 6 is an orally active, selective thyroid hormone receptor β (THR-β) agonist with EC50s of 0.03 μM and 0.22 μM for THR-β and THR-α, respectively. THR-β agonist 6 exhibits an xcellent liver-to-serum ratio of 93:1 in mice. THR-β agonist 6 has the potential for nonalcoholic steatohepatitis (NASH) research[1].

THR-β agonist 7
HY-160266 Get quote Ask for price
Description: THR-β agonist-1 (Example 2) is a THR-β agonist, with EC50 values of 52 nM and 1017 nM for THR-β and THR-α, respectively[1].

THR-β agonist 1
HY-142441 Get quote Ask for price
Description: THR-β Agonist 1 is a potent and selective agonist of THRβ. Thyroid hormone receptor mediates the physiological activity of thyroid hormones which plays a key role in normal growth and development of the body and in maintaining metabolic balance. THR-β Agonist 1 has the potential for the research of thyroid hormone receptor-related diseases (extracted from patent WO2021104288A1, compound 2)[1].

THR-β agonist 4
HY-142917 Get quote Ask for price
Description: THR-β agonist 4 is a potent agonist of THR-β. THR-β agonist 4 has the potential for the research of metabolic diseases such as obesity, hyperlipidemia, hypercholesterolemia, diabetes and other conditions such as steatosis and non-alcoholic steatohepatitis (NASH), atherosclerosis and other related conditions and diseases (extracted from patent WO2021143706A1, compound 72)[1].

THR-β agonist 2
HY-143613 Get quote Ask for price
Description: THR-β agonist 2 is a potent agonist of THR-β. THR-β agonist 2 has the potential for the research of metabolic diseases such as obesity, hyperlipidemia, hypercholesterolemia, diabetes and other conditions such as steatosis and non-alcoholic steatohepatitis (NASH), atherosclerosis and other related conditions and diseases (extracted from patent WO2021121210A1, compound 3)[1].

THR-β agonist 3
HY-143614 Get quote Ask for price
Description: THR-β agonist 3 is a potent agonist of THR-β. THR-β agonist 3 has the potential for the research of metabolic diseases such as obesity, hyperlipidemia, hypercholesterolemia, diabetes and other conditions such as steatosis and non-alcoholic steatohepatitis (NASH), atherosclerosis and other related conditions and diseases (extracted from patent WO2021129827A1, compound 6)[1].

THR-β agonist 5
T61759-10mg 10mg Ask for price
Description: THR-β agonist 5

THR-β agonist 5
T61759-1g 1g Ask for price
Description: THR-β agonist 5

THR-β agonist 5
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Description: THR-β agonist 5

THR-β agonist 5
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Description: THR-β agonist 5

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Description: THR-β agonist 5

THR-β agonist 4
T63515-10mg 10mg Ask for price
Description: THR-β agonist 4

THR-β agonist 4
T63515-1g 1g Ask for price
Description: THR-β agonist 4

THR-β agonist 4
T63515-1mg 1mg Ask for price
Description: THR-β agonist 4

THR-β agonist 4
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Description: THR-β agonist 4

THR-β agonist 4
T63515-5mg 5mg Ask for price
Description: THR-β agonist 4

THR-β agonist 3
T63697-10mg 10mg Ask for price
Description: THR-β agonist 3

THR-β agonist 3
T63697-1g 1g Ask for price
Description: THR-β agonist 3

THR-β agonist 3
T63697-1mg 1mg Ask for price
Description: THR-β agonist 3

THR-β agonist 3
T63697-50mg 50mg Ask for price
Description: THR-β agonist 3

THR-β agonist 3
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Description: THR-β agonist 3

THR-β agonist 1
T62570-10mg 10mg Ask for price
Description: THR-β agonist 1

THR-β agonist 1
T62570-1g 1g Ask for price
Description: THR-β agonist 1

THR-β agonist 1
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Description: THR-β agonist 1

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Description: THR-β agonist 1

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Description: THR-β agonist 1

THR-β agonist 2
T62594-10mg 10mg Ask for price
Description: THR-β agonist 2

THR-β agonist 2
T62594-1g 1g Ask for price
Description: THR-β agonist 2

THR-β agonist 2
T62594-1mg 1mg Ask for price
Description: THR-β agonist 2

THR-β agonist 2
T62594-50mg 50mg Ask for price
Description: THR-β agonist 2

THR-β agonist 2
T62594-5mg 5mg Ask for price
Description: THR-β agonist 2

Wnt/β-catenin agonist 1
HY-114321 10 mg
EUR 2543.33
Description: Wnt/β-catenin agonist 1 (compound 3f) is a Wnt/β-catenin signalling pathway agonist, with an EC50 of 0.27 μM[1].

Wnt/β-catenin agonist 3
HY-148055 10 mg
EUR 487.02
Description: Wnt/β-catenin agonist 3 (compound 98) is a Wnt/β-catenin signalling pathway agonist. Wnt/β-catenin agonist 3 can be used for the research of osteoporosis[1].

Wnt/β-catenin agonist 4
HY-151520 10 mg
EUR 432.91
Description: Wnt/β-catenin agonist 4 (Derivative 83) is an agonist of Wnt that activates Wnt/β-catenin signal transmission[1].

Wnt/β-catenin agonist 2
HY-141873 10 mg
EUR 1461.06
Description: Wnt/β-catenin agonist 2 is a potent Wnt agonist. Wnt/β-catenin agonist 2 activates Wnt/β-catenin signaling and can be used in the research of diseases related to the signal transduction[1]. (From patent WO2007078113A1, compound 39)

Wnt/β-catenin agonist 1
T13344-10mg 10mg Ask for price
Description: Wnt/β-catenin agonist 1

Wnt/β-catenin agonist 1
T13344-1g 1g Ask for price
Description: Wnt/β-catenin agonist 1

Wnt/β-catenin agonist 1
T13344-1mg 1mg Ask for price
Description: Wnt/β-catenin agonist 1

Wnt/β-catenin agonist 1
T13344-50mg 50mg Ask for price
Description: Wnt/β-catenin agonist 1

Wnt/β-catenin agonist 1
T13344-5mg 5mg Ask for price
Description: Wnt/β-catenin agonist 1

Wnt/β-catenin agonist 4
T60803-10mg 10mg Ask for price
Description: Wnt/β-catenin agonist 4

Wnt/β-catenin agonist 4
T60803-1g 1g Ask for price
Description: Wnt/β-catenin agonist 4

Wnt/β-catenin agonist 4
T60803-1mg 1mg Ask for price
Description: Wnt/β-catenin agonist 4

Wnt/β-catenin agonist 4
T60803-50mg 50mg Ask for price
Description: Wnt/β-catenin agonist 4

Wnt/β-catenin agonist 4
T60803-5mg 5mg Ask for price
Description: Wnt/β-catenin agonist 4

Wnt/β-catenin agonist 2
T41094-10mg 10mg Ask for price
Description: Wnt/β-catenin agonist 2

Wnt/β-catenin agonist 2
T41094-1g 1g Ask for price
Description: Wnt/β-catenin agonist 2

Wnt/β-catenin agonist 2
T41094-1mg 1mg Ask for price
Description: Wnt/β-catenin agonist 2

Wnt/β-catenin agonist 2
T41094-50mg 50mg Ask for price
Description: Wnt/β-catenin agonist 2

Wnt/β-catenin agonist 2
T41094-5mg 5mg Ask for price
Description: Wnt/β-catenin agonist 2

Wnt/β-catenin agonist 3 (hydrochloride)
HY-148055A 10 mg
EUR 91.99
Description: Wnt/β-catenin agonist 3 hydrochloride is a Wnt/β-catenin signalling pathway agonist. Wnt/β-catenin agonist 3 (compound 98) can be used for the research of osteoporosis[1].

Bid ELISA Kit| Mouse BH3 Interacting Domain Death Agonist ELISA
EF013466 96 Tests
EUR 826.8

Rat BH3 Interacting Domain Death Agonist ELISA Kit
MBS721688-48StripWellsCompetitive 48-Strip-Wells-(Competitive)
EUR 485

Rat BH3 Interacting Domain Death Agonist ELISA Kit
MBS721688-48StripWellsSandwich 48-Strip-Wells-(Sandwich)
EUR 485

Rat BH3 Interacting Domain Death Agonist ELISA Kit
MBS721688-5x96StripWellsCompetitive 5x96-Strip-Wells-(Competitive)
EUR 3020

Rat BH3 Interacting Domain Death Agonist ELISA Kit
MBS721688-96StripWellsCompetitive 96-Strip-Wells-(Competitive)
EUR 690

Rat BH3 Interacting Domain Death Agonist ELISA Kit
MBS721688-96StripWellsSandwich 96-Strip-Wells-(Sandwich)
EUR 690

Rat BH3 Interacting Domain Death Agonist ELISA kit
E01A10462 96T
EUR 700
Description: ELISA

Rat BH3 Interacting Domain Death Agonist ELISA kit
E02B0306-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rat BH3 Interacting Domain Death Agonist in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat BH3 Interacting Domain Death Agonist ELISA kit
E02B0306-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rat BH3 Interacting Domain Death Agonist in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat BH3 Interacting Domain Death Agonist ELISA kit
E02B0306-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rat BH3 Interacting Domain Death Agonist in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog BH3 Interacting Domain Death Agonist ELISA kit
E08B0306-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Canine BH3 Interacting Domain Death Agonist in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog BH3 Interacting Domain Death Agonist ELISA kit
E08B0306-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Canine BH3 Interacting Domain Death Agonist in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog BH3 Interacting Domain Death Agonist ELISA kit
E08B0306-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Canine BH3 Interacting Domain Death Agonist in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig BH3 Interacting Domain Death Agonist ELISA kit
E07B0306-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Porcine BH3 Interacting Domain Death Agonist in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig BH3 Interacting Domain Death Agonist ELISA kit
E07B0306-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Porcine BH3 Interacting Domain Death Agonist in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig BH3 Interacting Domain Death Agonist ELISA kit
E07B0306-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Porcine BH3 Interacting Domain Death Agonist in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Cat Bh3 Interacting Domain Death Agonist ELISA Kit
MBS084205-INQUIRE INQUIRE Ask for price

Rat Bh3 Interacting Domain Death Agonist ELISA Kit
MBS045681-10x96StripWells 10x96-Strip-Wells
EUR 6725

Rat Bh3 Interacting Domain Death Agonist ELISA Kit
MBS045681-48StripWells 48-Strip-Wells
EUR 550

Rat Bh3 Interacting Domain Death Agonist ELISA Kit
MBS045681-5x96StripWells 5x96-Strip-Wells
EUR 3420

Rat Bh3 Interacting Domain Death Agonist ELISA Kit
MBS045681-96StripWells 96-Strip-Wells
EUR 765

Rat BH3 Interacting Domain Death Agonist ELISA Kit
IRTBIDKT each
EUR 718
Description: Rat BH3 Interacting Domain Death Agonist ELISA Kit

Goat BH3 Interacting Domain Death Agonist ELISA kit
E01A45374 96T
EUR 700
Description: ELISA

Goat BH3 Interacting Domain Death Agonist ELISA kit
E06B0306-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Goat BH3 Interacting Domain Death Agonist in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat BH3 Interacting Domain Death Agonist ELISA kit
E06B0306-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Goat BH3 Interacting Domain Death Agonist in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat BH3 Interacting Domain Death Agonist ELISA kit
E06B0306-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Goat BH3 Interacting Domain Death Agonist in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Duck Bh3 Interacting Domain Death Agonist ELISA Kit
MBS087967-INQUIRE INQUIRE Ask for price

Goat Bh3 Interacting Domain Death Agonist ELISA Kit
MBS045425-INQUIRE INQUIRE Ask for price

Fish Bh3 Interacting Domain Death Agonist ELISA Kit
MBS045624-INQUIRE INQUIRE Ask for price

Cavy Bh3 Interacting Domain Death Agonist ELISA Kit
MBS036082-INQUIRE INQUIRE Ask for price

Goat BH3 Interacting Domain Death Agonist ELISA Kit
MBS737715-10x96StripWells 10x96-Strip-Wells
EUR 5685

Goat BH3 Interacting Domain Death Agonist ELISA Kit
MBS737715-48StripWells 48-Strip-Wells
EUR 485

Goat BH3 Interacting Domain Death Agonist ELISA Kit
MBS737715-5x96StripWells 5x96-Strip-Wells
EUR 3020

Goat BH3 Interacting Domain Death Agonist ELISA Kit
MBS737715-96StripWells 96-Strip-Wells
EUR 690

Bid ELISA Kit| Rat BH3-interacting domain death agonist ELISA Ki
EF017208 96 Tests
EUR 826.8

Human BH3 Interacting Domain Death Agonist ELISA Kit
MBS721310-48StripWellsCompetitive 48-Strip-Wells-(Competitive)
EUR 485

Human BH3 Interacting Domain Death Agonist ELISA Kit
MBS721310-48StripWellsSandwich 48-Strip-Wells-(Sandwich)
EUR 485

Human BH3 Interacting Domain Death Agonist ELISA Kit
MBS721310-5x96StripWellsCompetitive 5x96-Strip-Wells-(Competitive)
EUR 3020

Human BH3 Interacting Domain Death Agonist ELISA Kit
MBS721310-96StripWellsCompetitive 96-Strip-Wells-(Competitive)
EUR 690

Human BH3 Interacting Domain Death Agonist ELISA Kit
MBS721310-96StripWellsSandwich 96-Strip-Wells-(Sandwich)
EUR 690

Mouse BH3 Interacting Domain Death Agonist ELISA Kit
MBS721937-10x96StripWells 10x96-Strip-Wells
EUR 5685

Mouse BH3 Interacting Domain Death Agonist ELISA Kit
MBS721937-48StripWells 48-Strip-Wells
EUR 485

Mouse BH3 Interacting Domain Death Agonist ELISA Kit
MBS721937-5x96StripWells 5x96-Strip-Wells
EUR 3020

Mouse BH3 Interacting Domain Death Agonist ELISA Kit
MBS721937-96StripWells 96-Strip-Wells
EUR 690

BH3-Interacting Domain Death Agonist (BID) ELISA Kit
abx595062-96tests 96 tests
EUR 764.4

Human BH3 Interacting Domain Death Agonist ELISA kit
E01A1700 96T
EUR 700
Description: ELISA

Mouse BH3 Interacting Domain Death Agonist ELISA kit
E01A19203 96T
EUR 700
Description: ELISA

Mouse BH3 Interacting Domain Death Agonist ELISA kit
E03B0306-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Mouse BH3 Interacting Domain Death Agonist in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse BH3 Interacting Domain Death Agonist ELISA kit
E03B0306-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Mouse BH3 Interacting Domain Death Agonist in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse BH3 Interacting Domain Death Agonist ELISA kit
E03B0306-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Mouse BH3 Interacting Domain Death Agonist in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Sheep BH3 Interacting Domain Death Agonist ELISA kit
E01A97667 96T
EUR 700
Description: ELISA

Human BH3 Interacting Domain Death Agonist ELISA kit
E01B0306-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Human BH3 Interacting Domain Death Agonist in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human BH3 Interacting Domain Death Agonist ELISA kit
E01B0306-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Human BH3 Interacting Domain Death Agonist in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human BH3 Interacting Domain Death Agonist ELISA kit
E01B0306-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Human BH3 Interacting Domain Death Agonist in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Camel Bh3 Interacting Domain Death Agonist ELISA Kit
MBS089066-10x96StripWells 10x96-Strip-Wells
EUR 6725

Camel Bh3 Interacting Domain Death Agonist ELISA Kit
MBS089066-48StripWells 48-Strip-Wells
EUR 550

Camel Bh3 Interacting Domain Death Agonist ELISA Kit
MBS089066-5x96StripWells 5x96-Strip-Wells
EUR 3420

Camel Bh3 Interacting Domain Death Agonist ELISA Kit
MBS089066-96StripWells 96-Strip-Wells
EUR 765

Horse Bh3 Interacting Domain Death Agonist ELISA Kit
MBS009491-10x96StripWells 10x96-Strip-Wells
EUR 6725

Horse Bh3 Interacting Domain Death Agonist ELISA Kit
MBS009491-48StripWells 48-Strip-Wells
EUR 550

Horse Bh3 Interacting Domain Death Agonist ELISA Kit
MBS009491-5x96StripWells 5x96-Strip-Wells
EUR 3420

Horse Bh3 Interacting Domain Death Agonist ELISA Kit
MBS009491-96StripWells 96-Strip-Wells
EUR 765

Sheep Bh3 Interacting Domain Death Agonist ELISA Kit
MBS012456-10x96StripWells 10x96-Strip-Wells
EUR 6725

Sheep Bh3 Interacting Domain Death Agonist ELISA Kit
MBS012456-48StripWells 48-Strip-Wells
EUR 550

Sheep Bh3 Interacting Domain Death Agonist ELISA Kit
MBS012456-5x96StripWells 5x96-Strip-Wells
EUR 3420

Sheep Bh3 Interacting Domain Death Agonist ELISA Kit
MBS012456-96StripWells 96-Strip-Wells
EUR 765

Mouse Bh3 Interacting Domain Death Agonist ELISA Kit
MBS024701-10x96StripWells 10x96-Strip-Wells
EUR 6725

Mouse Bh3 Interacting Domain Death Agonist ELISA Kit
MBS024701-48StripWells 48-Strip-Wells
EUR 550

Mouse Bh3 Interacting Domain Death Agonist ELISA Kit
MBS024701-5x96StripWells 5x96-Strip-Wells
EUR 3420

Mouse Bh3 Interacting Domain Death Agonist ELISA Kit
MBS024701-96StripWells 96-Strip-Wells
EUR 765

Goose Bh3 Interacting Domain Death Agonist ELISA Kit
MBS014736-INQUIRE INQUIRE Ask for price

Human Bh3 Interacting Domain Death Agonist ELISA Kit
MBS023113-10x96StripWells 10x96-Strip-Wells
EUR 6725

Human Bh3 Interacting Domain Death Agonist ELISA Kit
MBS023113-48StripWells 48-Strip-Wells
EUR 550

Human Bh3 Interacting Domain Death Agonist ELISA Kit
MBS023113-5x96StripWells 5x96-Strip-Wells
EUR 3420

Human Bh3 Interacting Domain Death Agonist ELISA Kit
MBS023113-96StripWells 96-Strip-Wells
EUR 765

Mouse BH3 Interacting Domain Death Agonist ELISA Kit
IMSBIDKT each
EUR 616
Description: Mouse BH3 Interacting Domain Death Agonist ELISA Kit

Human BH3 Interacting Domain Death Agonist ELISA Kit
IHUBIDKT each
EUR 667
Description: Human BH3 Interacting Domain Death Agonist ELISA Kit

Rat BH3-interacting domain death agonist ELISA Kit
MBS289579-10x96StripWells 10x96-Strip-Wells
EUR 4080

Rat BH3-interacting domain death agonist ELISA Kit
MBS289579-48StripWells 48-Strip-Wells
EUR 390

Rat BH3-interacting domain death agonist ELISA Kit
MBS289579-5x96StripWells 5x96-Strip-Wells
EUR 2220

Rat BH3-interacting domain death agonist ELISA Kit
MBS289579-96StripWells 96-Strip-Wells
EUR 520

Pig BH3-interacting domain death agonist ELISA Kit
MBS2886061-10x96StripWells 10x96-Strip-Wells
EUR 4630

Pig BH3-interacting domain death agonist ELISA Kit
MBS2886061-48StripWells 48-Strip-Wells
EUR 440

Pig BH3-interacting domain death agonist ELISA Kit
MBS2886061-5x96StripWells 5x96-Strip-Wells
EUR 2480

Pig BH3-interacting domain death agonist ELISA Kit
MBS2886061-96StripWells 96-Strip-Wells
EUR 580

Sheep BH3 Interacting Domain Death Agonist ELISA Kit
MBS738222-10x96StripWells 10x96-Strip-Wells
EUR 5685

Sheep BH3 Interacting Domain Death Agonist ELISA Kit
MBS738222-48StripWells 48-Strip-Wells
EUR 485

Sheep BH3 Interacting Domain Death Agonist ELISA Kit
MBS738222-5x96StripWells 5x96-Strip-Wells
EUR 3020

Sheep BH3 Interacting Domain Death Agonist ELISA Kit
MBS738222-96StripWells 96-Strip-Wells
EUR 690

Rat BH3-interacting domain death agonist ELISA Kit
MBS762685-10x96StripWells 10x96-Strip-Wells
EUR 3900

Rat BH3-interacting domain death agonist ELISA Kit
MBS762685-48StripWells 48-Strip-Wells
EUR 340

Rat BH3-interacting domain death agonist ELISA Kit
MBS762685-5x96StripWells 5x96-Strip-Wells
EUR 2045

Rat BH3-interacting domain death agonist ELISA Kit
MBS762685-96StripWells 96-Strip-Wells
EUR 455

Rat BH3-interacting domain death agonist ELISA Kit
MBS9425901-5x96Tests 5x96Tests
EUR 2820

Rat BH3-interacting domain death agonist ELISA Kit
MBS9425901-96Tests 96Tests
EUR 615

Mouse BH3 Interacting Domain Death Agonist ELISA Kit
MBS765103-10x96StripWells 10x96-Strip-Wells
EUR 3900

Mouse BH3 Interacting Domain Death Agonist ELISA Kit
MBS765103-48StripWells 48-Strip-Wells
EUR 340

Mouse BH3 Interacting Domain Death Agonist ELISA Kit
MBS765103-5x96StripWells 5x96-Strip-Wells
EUR 2045

Mouse BH3 Interacting Domain Death Agonist ELISA Kit
MBS765103-96StripWells 96-Strip-Wells
EUR 455

Rat BH3 interacting domain death agonist,Bid ELISA Kit
CN-01707R1 96T
EUR 556.8

Rat BH3 interacting domain death agonist,Bid ELISA Kit
CN-01707R2 48T
EUR 375.6

Pig BH3 Interacting Domain Death Agonist (BID) ELISA Kit
abx360959-100g 100 µg
EUR 687.5

Pig BH3 Interacting Domain Death Agonist (BID) ELISA Kit
abx360959-96tests 96 tests
EUR 990

Rat BH3 Interacting Domain Death Agonist (Bid) ELISA Kit
abx155258-100l 100 µl
EUR 675

Rat BH3 Interacting Domain Death Agonist (Bid) ELISA Kit
20-abx155258
  • Ask for price
  • Ask for price
  • Ask for price
  • 96 tests
  • 5 × 96 tests
  • 10 × 96 tests

Rat BH3 Interacting Domain Death Agonist (BID) ELISA Kit
abx256314-1096tests 10 × 96 tests Ask for price

Rat BH3 Interacting Domain Death Agonist (BID) ELISA Kit
abx256314-596tests 5 × 96 tests Ask for price

Rat BH3 Interacting Domain Death Agonist (BID) ELISA Kit
abx256314-96tests 96 tests
EUR 531.25

Rat BH3 Interacting Domain Death Agonist (BID) ELISA Kit
abx572028-96tests 96 tests
EUR 848.4

Two days after ischemia BAY60-6583 diminished blood cell infiltration within the ischemic cortex. The current examine signifies that A2B receptors stimulation can attenuate the neuroinflammation that develops after ischemia, suggesting that A2B receptors could characterize a brand new attention-grabbing pharmacological goal to guard from degeneration after mind ischemia.

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